Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

@article{Seto2011RabGR,
  title={Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.},
  author={Shintaro Seto and Kunio Tsujimura and Yukio Koide},
  journal={Traffic},
  year={2011},
  volume={12 4},
  pages={407-20}
}
Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that can replicate within infected macrophages. The ability of M. tb to arrest phagosome maturation is believed to facilitate its intracellular multiplication. Rab GTPases regulate membrane trafficking, but details of how Rab GTPases regulate phagosome maturation and how M. tb modulates their localization during inhibiting phagolysosome biogenesis remain elusive. We compared the localization of 42 distinct Rab GTPases to phagosomes… CONTINUE READING
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