Rab GTPases implicated in inherited and acquired disorders.

Abstract

The endocytotic machinery imports, transports and exports receptors and associated molecules between the plasma membrane and various cytoplasmic chambers resulting in selective recycling, degradation, or secretion of molecules and signaling complexes. Trafficking of receptors, growth factors, nutrients, cytokines, integrins as well as pathogens dictates the… (More)
DOI: 10.1016/j.semcdb.2010.12.005

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