Rab GAP cascade regulates dynamics of Ypt6 in the Golgi traffic.

  title={Rab GAP cascade regulates dynamics of Ypt6 in the Golgi traffic.},
  author={Yasuyuki Suda and Kazuo Kurokawa and Ryogo Hirata and Akihiko Nakano},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={110 47},
The Golgi apparatus functions as the central station of membrane traffic in cells, where newly synthesized proteins moving along the secretory pathway merge with proteins recycled from subsequent membrane organelles such as endosomes. A series of Rab GTPases act consecutively and in concert with the maturation of cis- to-trans cisternae of the Golgi apparatus. Rab GTPases control various steps in intracellular membrane traffic by recruiting downstream effector proteins. Here, we report the… CONTINUE READING
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