Rab 23 is expressed in the glomerulus and plays a role in the development of focal segmental glomerulosclerosis.

@article{Huang2008Rab2I,
  title={Rab 23 is expressed in the glomerulus and plays a role in the development of focal segmental glomerulosclerosis.},
  author={Tzu-Hao Huang and Hao-Ai Shui and Shuk-Man Ka and B Tang and Tai-Kuang Chao and Jin-Shuen Chen and Yuh-Feng Lin and Ann Chen},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2008},
  volume={24 3},
  pages={
          743-54
        }
}
  • Tzu-Hao Huang, Hao-Ai Shui, +5 authors Ann Chen
  • Published in
    Nephrology, dialysis…
    2008
  • Biology, Medicine
  • BACKGROUND Rab23, a member of the Rab family of small GTPase, has a function in antagonizing sonic hedgehog signal transduction. Both Rab-family and hedgehog-related proteins are involved in sclerosis and fibrosis in certain pathological states, but their roles in focal segmental glomerulosclerosis (FSGS) remain unclear. METHODS The FSGS model was established in Balb/c mice by a single injection of adriamycin. Serum, urine and mice kidneys were collected on Days 0, 7, 15 and 20. Western blot… CONTINUE READING

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