RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.

@article{Grtsch2012RWDD1IW,
  title={RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.},
  author={Helga Gr{\"o}tsch and Marlene Kunert and Katrin A. Mooslehner and Zhigang Gao and Dagmar Struve and Ieuan A Hughes and Olaf Hiort and Ralf Werner},
  journal={Molecular and cellular endocrinology},
  year={2012},
  volume={358 1},
  pages={53-62}
}
During embryogenesis, the development of the male genital is dependent on androgens. Their actions are mediated by the androgen receptor (AR), which functions as a transcription factor. To identify AR coregulators that support AR action during the critical time window of androgen-dependent development in the genital tubercle of male mice, we performed yeast… CONTINUE READING