RVD in principal and intercalated cells of rabbit cortical collecting tubule.

@article{Strange1988RVDIP,
  title={RVD in principal and intercalated cells of rabbit cortical collecting tubule.},
  author={Kevin Strange},
  journal={The American journal of physiology},
  year={1988},
  volume={255 5 Pt 1},
  pages={C612-21}
}
  • Kevin Strange
  • Published 1988 in The American journal of physiology
Cells of the rabbit renal cortical collecting tubule possess significant regulatory volume decrease (RVD) capabilities. After a 100-mosmol/kg reduction in peritubular osmolality, principal and intercalated cells swell 40-45 and 30-35%, respectively, and immediately activate RVD mechanisms. Both cell types downregulate their volume to within 5-6% of control… CONTINUE READING