RUNX3 plays a tumor suppressor role by inhibiting cell migration, invasion and angiogenesis in oral squamous cell carcinoma.

@article{Zhou2017RUNX3PA,
  title={RUNX3 plays a tumor suppressor role by inhibiting cell migration, invasion and angiogenesis in oral squamous cell carcinoma.},
  author={Wei-na Zhou and Yi-fei Du and Jin Feng Bai and Xiao-meng Song and Yang Zheng and Hua Yuan and Wei Zhang and Zheng-dong Zhang and Yu-Nong Wu},
  journal={Oncology reports},
  year={2017},
  volume={38 4},
  pages={
          2378-2386
        }
}
Although aberrant expression of Runt-related transcription factor 3 (RUNX3) contributes to tumor progression and metastasis in a number of carcinomas, the status of RUNX3 and its correlation with prognosis in oral squamous cell carcinomas (OSCC) are still controversial. The aim of present study was to investigate the function of RUNX3 in OSCC and the underlying molecular mechanisms. Tissue microarray (TMA) consisting of 232 OSCC specimens was used to detect the expression of RUNX3 by… CONTINUE READING

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