RUNX factors in development: lessons from invertebrate model systems.

@article{Braun2009RUNXFI,
  title={RUNX factors in development: lessons from invertebrate model systems.},
  author={Toby Braun and Alison Woollard},
  journal={Blood cells, molecules & diseases},
  year={2009},
  volume={43 1},
  pages={
          43-8
        }
}
Runt-related (RUNX) transcription factors are evolutionarily conserved regulators of cell proliferation, differentiation and stem cell maintenance. They are critical for the correct development and function of a variety of human tissues, including during haematopoiesis. RUNX genes regulate various aspects of proliferation control, stem cell maintenance, lineage commitment and regulation of differentiation; disruptions in the correct function of RUNX genes have been associated with human… CONTINUE READING
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