RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation.

@article{Pastva2005RU486BT,
  title={RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation.},
  author={Amy Pastva and Kim Estell and Trenton R. Schoeb and Lisa M. Schwiebert},
  journal={Brain, behavior, and immunity},
  year={2005},
  volume={19 5},
  pages={413-22}
}
In an ovalbumin (OVA)-driven murine model of allergic pulmonary inflammation, we have shown previously that moderate-intensity aerobic exercise training attenuates inflammatory responses, disease progression, and NF-kappaB activation within the sensitized lung. Glucocorticoids (GCs), potent anti-inflammatory agents, have been shown to alter transcriptional events that are important in asthmatic pathogenesis, such as NF-kappaB activation. Notably, exercise training can alter the production and… CONTINUE READING
15 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…