RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.

  title={RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.},
  author={Maulik R. Patel and Kang Shen},
  volume={323 5920},
As fundamental units of neuronal communication, chemical synapses are composed of presynaptic and postsynaptic specializations that form at specific locations with defined shape and size. Synaptic assembly must be tightly regulated to prevent overgrowth of the synapse size and number, but the molecular mechanisms that inhibit synapse assembly are poorly understood. We identified regulator of synaptogenesis-1 (RSY-1) as an evolutionarily conserved molecule that locally antagonized presynaptic… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 25 extracted citations


Publications referenced by this paper.
Showing 1-10 of 18 references


  • M D Muzumdar, B Tasic, K Miyamichi, L Li, L Luo
  • Genesis
  • 2007

Mol. Cell. Proteomics

  • D Blanchard, H Hutter, J Fleenor, A Fire
  • Mol. Cell. Proteomics
  • 2006

Nat. Neurosci

  • M R Patel
  • Nat. Neurosci
  • 2006


  • S W Flavell
  • Science
  • 2006

Annu. Rev. Neurosci

  • C L Waites, A M Craig, C C Garner
  • Annu. Rev. Neurosci
  • 2005

J. Neurosci

  • S L Deken
  • J. Neurosci
  • 2005

Mol. Vis

  • J H Joo
  • Mol. Vis
  • 2005


  • P Van Roessel, D A Elliott, I M Robinson, A Prokop, A H Brand
  • Cell
  • 2004

Curr. Opin. Neurobiol

  • M Zhen, Y Jin
  • Curr. Opin. Neurobiol
  • 2004

Mol. Cell. Biol

  • R Alpatov
  • Mol. Cell. Biol
  • 2004

Similar Papers

Loading similar papers…