RS-22A, B and C: new macrolide antibiotics from Streptomyces violaceusniger. I. Taxonomy, fermentation, isolation and biological activities.

Abstract

Three novel 36-membered macrolide antibiotics, RS-22A, B and C produced by Streptomyces violaceusniger have been isolated. These antibiotics were purified from an acetone extract of the mycelia followed by butanol extraction, centrifugal partition chromatography and HPLC. RS-22A, B, C showed antimicrobial activity against fungi and Gram-positive bacteria. 

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Cite this paper

@article{Ubukata1995RS22ABA, title={RS-22A, B and C: new macrolide antibiotics from Streptomyces violaceusniger. I. Taxonomy, fermentation, isolation and biological activities.}, author={Manabu Ubukata and Naomasa Shiraishi and Kimie Kobinata and Takafumi Kudo and Iwao Yamaguchi and Hirotaka Osada and Ying Chun Shen and Kaichi Isono}, journal={The Journal of antibiotics}, year={1995}, volume={48 4}, pages={289-92} }