RREB1 transcription factor splice variants in urologic cancer.


RREB1 is an alternatively spliced transcription factor implicated in Ras signaling and cancer. Little is known about the expression of RREB1 isoforms in cell lines or human tumors, or about the clinical relevance of the latter. We have developed tools for IHC of RREB1 protein isoform-specific amplification of RREB1 mRNA and selective knockdown of RREB1… (More)
DOI: 10.1016/j.ajpath.2011.03.038


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