RP105 is associated with MD-1 and transmits an activation signal in human B cells.

@article{Miura1998RP105IA,
  title={RP105 is associated with MD-1 and transmits an activation signal in human B cells.},
  author={Yoshihiro Miura and Rintaro Shimazu and Kensuke Miyake and Sachiko Akashi and Hirotaka Ogata and Yoshio Yamashita and Yutaka Narisawa and Masao Kimoto},
  journal={Blood},
  year={1998},
  volume={92 8},
  pages={2815-22}
}
RP105 was originally discovered as a mouse B-cell surface molecule that transmits an activation signal. The signal leads to resistance against irradiation-induced apoptosis and massive B-cell proliferation. Recently, we found that mouse RP105 is associated with another molecule, MD-1. We have isolated here the human MD-1 cDNA. We show that human MD-1 is also associated with human RP105 and has an important role in cell surface expression of RP105. We also describe a monoclonal antibody (MoAb… CONTINUE READING

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