• Chemistry
  • Published 2015

RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF CLINDAMYCIN PHOSPHATE AND CLOTRIMAZOLE IN PHARMACEUTICAL DOSAGE FORMS Original Article

@inproceedings{Sudhakar2015RPHPLCMD,
  title={RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF CLINDAMYCIN PHOSPHATE AND CLOTRIMAZOLE IN PHARMACEUTICAL DOSAGE FORMS Original Article},
  author={Muvvala Sudhakar and K. Vijayasri and Sridhar Siddiraju and M Nirupama},
  year={2015}
}
Objective: The aim of this work was to develop and validate a simple Reverse Phase-High Performance Liquid Chromatography method for the simultaneous estimation of Clindamycin and Clotrimazole in pharmaceutical dosage forms. Methods: The mobile phase consists of phosphate buffer and Acetonitrile in the ratio of (48:52) with gradient programming, Hypersil BDS (250×4.6 mm,5µ) column used as stationary phase with a flow rate of 1 ml/min, injection volume 10 µl and the run time was 10 min… CONTINUE READING