ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone.

Abstract

Free radical-triggered tissue damage is believed to play an essential role in a variety of human diseases. Pentachlorophenol (PCP) is applied as a pesticide worldwide in both industries and homes. It is used extensively as a biocide and wood preservative. Tetrachlorohydroquinone (TCHQ) was proved as a major toxic metabolite of PCP, contributing the release… (More)
DOI: 10.1021/tx500487w

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Cite this paper

@article{Chen2015ROStriggeredSP, title={ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone.}, author={Hsiu-Min Chen and Yu-Hsuan Lee and Ying-Jan Wang}, journal={Chemical research in toxicology}, year={2015}, volume={28 3}, pages={339-50} }