ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.

@article{Shabalina2014ROSPI,
  title={ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.},
  author={Irina G Shabalina and Marek Vrback{\'y} and Alena Pecinov{\'a} and Anastasia V. Kalinovich and Zdeněk Drahota and Josef Hou{\vs}těk and Tomas Mracek and Barbara A Cannon and Jan Nedergaard},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1837 12},
  pages={2017-2030}
}
Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The issue is of principal significance, as it can be seen as a proof- or disproof-of-principle concerning the ability of any protein to diminish ROS production through membrane depolarization. We therefore undertook a comprehensive investigation of the significance of UCP1 for ROS production, by comparing the ROS production in brown-fat mitochondria isolated from wildtype mice (that display… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
15 Citations
81 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 81 references

N

  • I. G. Shabalina
  • Petrovic, J.M. de Jong, A.V. Kalinovich, B…
  • 2013
Highly Influential
6 Excerpts

D

  • M. Nabben, I. G. Shabalina, E. Moonen-Kornips
  • van Beurden, B. Cannon, P. Schrauwen, J…
  • 2011
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…