ROS induced CXCR4 signaling regulates mantle cell lymphoma (MCL) cell survival and drug resistance in the bone marrow microenvironment via autophagy

Abstract

Purpose: Patients with advanced stages of MCL have a poor prognosis after standard therapies. MCL cells in those patients often spread into tissues other than lymph nodes, such as the bone marrow. Apart from directed migration and homing, there is little understanding of the function of the CXCR4/SDF1 signaling axis in MCL. In this report, we aim to… (More)

Topics

1 Figure or Table

Statistics

05010020162017
Citations per Year

Citation Velocity: 24

Averaging 24 citations per year over the last 2 years.

Learn more about how we calculate this metric in our FAQ.

Cite this paper

@inproceedings{Chen2015ROSIC, title={ROS induced CXCR4 signaling regulates mantle cell lymphoma (MCL) cell survival and drug resistance in the bone marrow microenvironment via autophagy}, author={Zheng Chen and Albert E. K. Teo and Nami McCarty}, year={2015} }