RORγt is dispensable for the development of intestinal mucosal T cells

To examine the origin of intestinal mucosal T cells and, in particular, unconventional CD8αα+ T cells, we have undertaken a thorough analysis of the gut immune compartment in euthymic and athymic mice carrying either wild-type or mutant transcription factor retinoic acid-related orphan receptor-γt (RORγt). We identified a previously unrealized complexity of… (More)