RORγ antagonists and inverse agonists: a patent review

@article{Bronner2017RORAA,
  title={ROR$\gamma$ antagonists and inverse agonists: a patent review},
  author={Sarah M Bronner and Jason R. Zbieg and James J. Crawford},
  journal={Expert Opinion on Therapeutic Patents},
  year={2017},
  volume={27},
  pages={101 - 112}
}
ABSTRACT Introduction: The transcription factor RORγ plays a critical role in the expression of pro-inflammatory cytokine interleukin IL-17 and is therefore an attractive target for the treatment of inflammatory diseases. Interest in this molecular target has been heightened by the advancement of orally and topically administered RORγ modulators into clinical trials. Areas covered: The present review seeks to summarize published patent applications from assignee companies that have disclosed… 
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