RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma

@article{Catenacci2011RONI,
  title={RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma},
  author={Daniel V T Catenacci and Gustavo M. Cervantes and Soheil Yala and E Andrea Nelson and Essam El-Hashani and Rajani Kanteti and Mohamed El Dinali and Rifat Hasina and Johannes Braegelmann and Tanguy Y. Seiwert and Michele Sanicola and Les Henderson and Tatyana A. Grushko and Olufunmilayo I. Olopade and Theodore Karrison and Yung-Jue Bang and Woo Ho Kim and Maria S Tretiakova and Everett E. Vokes and David A. Frank and Hedy Lee Kindler and Heather Huet and Ravi Salgia},
  journal={Cancer Biology & Therapy},
  year={2011},
  volume={12},
  pages={46 - 9}
}
  • Daniel V T Catenacci, Gustavo M. Cervantes, +20 authors Ravi Salgia
  • Published 2011
  • Biology, Medicine
  • Cancer Biology & Therapy
  • RON (MST1R) is one of two members of the MET receptor tyrosine kinase family, along with parent receptor MET. RON has a putative role in several cancers, but its expression and function is poorly characterized in gastroesophageal adenocarcinoma. A recognized functional role of MET tyrosine kinase in gastroesophageal cancer has led to early phase clinical trials using MET inhibitors, with unimpressive results. Therefore, the role of RON in gastroesophageal cancer, as well as its role in… CONTINUE READING

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