ROHHAD syndrome and evolution of sleep disordered breathing

  title={ROHHAD syndrome and evolution of sleep disordered breathing},
  author={Diana Reppucci and Jill K Hamilton and E. Ann Yeh and Sherri Lynne Katz and Suhail Al-Saleh and Indra Narang},
  booktitle={Orphanet journal of rare diseases},
BACKGROUND Rapid-onset obesity with hypothalamic dysfunction, hypoventilation and autonomic dysregulation (ROHHAD) is a rare disease with a high mortality rate. Although nocturnal hypoventilation (NH) is central to ROHHAD, the evolution of sleep disordered breathing (SDB) is not well studied. The aim of the study was to assess early manifestations of SDB and their evolution in ROHHAD syndrome. METHODS Retrospective study of children with ROHHAD at two Canadian centers. All children with… CONTINUE READING
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