ROCKs: multifunctional kinases in cell behaviour
@article{Riento2003ROCKsMK, title={ROCKs: multifunctional kinases in cell behaviour}, author={Kirsi Riento and Anne J. Ridley}, journal={Nature Reviews Molecular Cell Biology}, year={2003}, volume={4}, pages={446-456} }
ROCKs, or Rho kinases, are serine/threonine kinases that are involved in many aspects of cell motility, from smooth-muscle contraction to cell migration and neurite outgrowth. Recent experiments have defined new functions of ROCKs in cells, including centrosome positioning and cell-size regulation, which might contribute to various physiological and pathological states.
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