ROC curves in clinical chemistry: uses, misuses, and possible solutions.

@article{Obuchowski2004ROCCI,
  title={ROC curves in clinical chemistry: uses, misuses, and possible solutions.},
  author={Nancy A. Obuchowski and Michael L. Lieber and Frank Wians},
  journal={Clinical chemistry},
  year={2004},
  volume={50 7},
  pages={1118-25}
}
BACKGROUND ROC curves have become the standard for describing and comparing the accuracy of diagnostic tests. Not surprisingly, ROC curves are used often by clinical chemists. Our aims were to observe how the accuracy of clinical laboratory diagnostic tests is assessed, compared, and reported in the literature; to identify common problems with the use of ROC curves; and to offer some possible solutions. METHODS We reviewed every original work using ROC curves and published in Clinical… CONTINUE READING