RNase Y is responsible for uncoupling the expression of translation factor IF3 from that of the ribosomal proteins L35 and L20 in Bacillus subtilis.

@article{Bruscella2011RNaseYI,
  title={RNase Y is responsible for uncoupling the expression of translation factor IF3 from that of the ribosomal proteins L35 and L20 in Bacillus subtilis.},
  author={Patrice Bruscella and Karen Shahbabian and Soumaya Laalami and Harald Putzer},
  journal={Molecular microbiology},
  year={2011},
  volume={81 6},
  pages={1526-41}
}
RNase Y is a novel endoribonuclease affecting global mRNA metabolism. We show that this nuclease affects the expression of the Bacillus subtilis infC-rpmI-rplT operon, encoding translation initiation factor IF3 and the ribosomal proteins L35 and L20. This operon is autoregulated by a complex L20-dependent transcription attenuation mechanism. L20 binds to a phylogenetically conserved domain on the 5' untranslated region of the infC mRNA which mimics the L20 binding sites on 23S rRNA. We have… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…