RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E.

@article{Ow2003RNaseGO,
  title={RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E.},
  author={Maria C. Ow and Tariq Perwez and Sidney R. Kushner},
  journal={Molecular microbiology},
  year={2003},
  volume={49 3},
  pages={607-22}
}
RNase G (rng) is an E. coli endoribonuclease that is homologous to the catalytic domain of RNase E (rne), an essential protein that is a major participant in tRNA maturation, mRNA decay, rRNA processing and M1 RNA processing. We demonstrate here that whereas RNase G inefficiently participates in the degradation of mRNAs and the processing of 9S rRNA, it is not involved in either tRNA or M1 RNA processing. This conclusion is supported by the fact that inactivation of RNase G alone does not… CONTINUE READING