RNase E plays an essential role in the maturation of Escherichia coli tRNA precursors.

@article{Li2002RNaseEP,
  title={RNase E plays an essential role in the maturation of Escherichia coli tRNA precursors.},
  author={Zhongwei Li and Murray P. Deutscher},
  journal={RNA},
  year={2002},
  volume={8 1},
  pages={97-109}
}
Conversion of tRNA precursors to their mature forms requires the action of both endo- and exoribonucleases. Although studies over many years identified the endoribonuclease, RNase P, and several exoribonucleases as the enzymes responsible for generating the mature 5' and 3' termini, respectively, of Escherichia coli tRNAs, relatively little is known about how tRNAs are separated from long multimeric or multifunction transcripts, or from long leader and trailer sequences. To examine this… CONTINUE READING