RNP export is mediated by structural reorganization of the nuclear pore basket.

@article{Kiseleva1996RNPEI,
  title={RNP export is mediated by structural reorganization of the nuclear pore basket.},
  author={Elena Kiseleva and Martin W. Goldberg and Bertil Daneholt and Terence D. Allen},
  journal={Journal of molecular biology},
  year={1996},
  volume={260 3},
  pages={304-11}
}
Messenger RNA leaves the cell nucleus as ribonucleoprotein (RNP) particles. The nucleocytoplasmic translocation of the particles takes place through the nuclear pore complex (NPC) and includes two steps: binding to the NPC and transit through its central channel. The NPC basket is a fishtrap-like component of NPC facing the nucleoplasm. Its position in the NPC strongly suggests that it has an important role in the initial steps of macromolecular export from the nucleus. Here we report a cyclic… CONTINUE READING
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