RNAs of the human chromosome 15q11-q13 imprinted region.

  title={RNAs of the human chromosome 15q11-q13 imprinted region.},
  author={Stormy J Chamberlain},
  journal={Wiley interdisciplinary reviews. RNA},
  volume={4 2},
The human chromosome 15q11-q13 region hosts a wide variety of coding and noncoding RNAs, and is also the site of nearly every imaginable type of RNA processing. To deepen the intrigue, the transcripts in the human chromosome 15q11-q13 region are subject to regulation by genomic imprinting, and some of these transcripts are imprinted in a tissue-specific manner. As the region is critically important for three human neurogenetic disorders, Angelman syndrome, Prader-Willi syndrome, and 15q… CONTINUE READING