RNAs from two independently isolated defective interfering particles of Sindbis virus contain a cellular tRNA sequence at their 5' ends.

@article{Monroe1983RNAsFT,
  title={RNAs from two independently isolated defective interfering particles of Sindbis virus contain a cellular tRNA sequence at their 5' ends.},
  author={Stephan S Monroe and Sondra Schlesinger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1983},
  volume={80 11},
  pages={3279-83}
}
Defective interfering (DI) particles are deletion mutants that interfere specifically with the replication of homologous standard virus. We have determined the 5'-terminal nucleotide sequences of two DI RNA populations by the following methods: (i) cloning of the cDNA from one of the DI RNA populations and sequencing a representative clone, and (ii) using both DI RNA populations as templates for preparing primer-directed cDNA transcripts and sequencing these transcripts. The 5' terminal… CONTINUE READING