RNAi therapeutics for CNS disorders.

  title={RNAi therapeutics for CNS disorders.},
  author={Ryan L. Boudreau and Beverly L. Davidson},
  journal={Brain research},
RNA interference (RNAi) is a process of sequence-specific gene silencing and serves as a powerful molecular tool to manipulate gene expression in vitro and in vivo. RNAi technologies have been applied to study gene function and validate drug targets. Researchers are investigating RNAi-based compounds as novel therapeutics to treat a variety of human diseases that are currently lacking sufficient treatment. To date, numerous studies support that RNAi therapeutics can improve disease phenotypes… CONTINUE READING

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