RNAi-based nanomedicines for targeted personalized therapy.

@article{Daka2012RNAibasedNF,
  title={RNAi-based nanomedicines for targeted personalized therapy.},
  author={Ala Daka and Dan Peer},
  journal={Advanced drug delivery reviews},
  year={2012},
  volume={64 13},
  pages={1508-21}
}
RNA interference (RNAi) has just made it through the pipeline to clinical trials. However, in order for RNAi to serve as an ideal personalized therapeutics and be clinically approved-safe, specific, and potent strategies must be devised for efficient delivery of RNAi payloads to specific cell types, which despite the immense potential, remains a challenge. Through evaluating the recent reported studies in this field, we introduce the progress in designing targeted nano-scaled strategies that… CONTINUE READING
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