RNAi Therapy: Antibodies guide the way

  title={RNAi Therapy: Antibodies guide the way},
  author={Mouldy Sioud},
  journal={Gene Therapy},
In a recent issue of Nature Biotechnology, Song et al showed that small interfering RNAs (siRNAs) can be delivered into a target cell population through antibody-mediated endocytosis. Several diseases such as cancers are a difficult target for any therapeutic strategy; therefore, there is a continuous search for new approaches. The use of siRNAs to target mRNAs for degradation through the biologically conserved RNA interference (RNAi) pathway is one such approach that is receiving increasing… CONTINUE READING

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