RNAIII-inhibiting peptide affects biofilm formation in a rat model of staphylococcal ureteral stent infection.

@article{Cirioni2007RNAIIIinhibitingPA,
  title={RNAIII-inhibiting peptide affects biofilm formation in a rat model of staphylococcal ureteral stent infection.},
  author={Oscar Cirioni and Roberto Ghiselli and Daniele Minardi and Fiorenza Orlando and Federico Mocchegiani and C. A. Di Silvestri and Giovanni Muzzonigro and Vittorio Saba and Giorgio Scalise and Naomi Balaban and Andrea Giacometti},
  journal={Antimicrobial agents and chemotherapy},
  year={2007},
  volume={51 12},
  pages={4518-20}
}
Ureteral stents coated with the quorum-sensing inhibitor RNAIII-inhibiting peptide (RIP) were implanted in rat bladders and shown to suppress Staphylococcus aureus formation on the stent and in urine and was especially effective when combined with teicoplanin. Coating ureteral stents with RIP thus increases the efficacy of teicoplanin in preventing ureteral… CONTINUE READING