RNA transport and localized protein synthesis in neurological disorders and neural repair.

@article{Wang2007RNATA,
  title={RNA transport and localized protein synthesis in neurological disorders and neural repair.},
  author={Wenlan Wang and Erna A. van Niekerk and Dianna E Willis and Jeffery L Twiss},
  journal={Developmental neurobiology},
  year={2007},
  volume={67 9},
  pages={1166-82}
}
Neural cells are able to finely tune gene expression through post-transcriptional mechanisms. Localization of mRNAs to subcellular regions has been detected in neurons, oligodendrocytes, and astrocytes providing these domains with a locally renewable source of proteins. Protein synthesis in dendrites has most frequently been associated with synaptic plasticity, while axonally synthesized proteins appear to facilitate pathfinding and injury responses. For oligodendrocytes, mRNAs encoding several… CONTINUE READING

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