RNA transcripts of full-length cDNA clones of rabbit hepatitis E virus are infectious in rabbits.

@article{Cossaboom2014RNATO,
  title={RNA transcripts of full-length cDNA clones of rabbit hepatitis E virus are infectious in rabbits.},
  author={Caitlin M. Cossaboom and Y. Wayne Huang and Danielle M. Yugo and Scott P. Kenney and Pablo Pi{\~n}eyro and Shannon R. Matzinger and Connie Lynn Heffron and Frank William Pierson and Xiang-Jin Meng},
  journal={The Journal of general virology},
  year={2014}
}
Hepatitis E virus (HEV), the causative agent of hepatitis E, is a single-stranded positive-sense RNA virus belonging to the family Hepeviridae. At least four genotypes of the family infect humans: genotypes 1 and 2 are transmitted to humans through contaminated water, while genotypes 3 and 4 are zoonotic and have animal reservoirs. A novel strain of HEV recently identified in rabbits is a distant member of genotype 3, and thus poses a potential risk of zoonotic transmission to humans. The… CONTINUE READING

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