RNA trans-splicing in Fasciola hepatica. Identification of a spliced leader (SL) RNA and SL sequences on mRNAs.

@article{Davis1994RNATI,
  title={RNA trans-splicing in Fasciola hepatica. Identification of a spliced leader (SL) RNA and SL sequences on mRNAs.},
  author={Roger E Davis and Harinder Singh and Christopher W. Botka and Chris R Hardwick and M Ashraf el Meanawy and Julieta Villanueva},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 31},
  pages={20026-30}
}
We have identified a new spliced leader (SL) in Fasciola hepatica by characterizing the 5'-terminal sequences of its enolase mRNA, an mRNA also trans-spliced in the flatworm Schistosoma mansoni (Rajkovic, A., Davis, R.E., Simonsen, J.N., and Rottman, F.M. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 8879-8883). This 37-nucleotide spliced leader is at the 5' ends of multiple Fasciola mRNAs and is likely to be derived from the 5' terminus of a nonpolyadenylated, 108-nucleotide RNA with a… CONTINUE READING

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A spliced leader in Fasciola indicates that trans - splicing is likely to be a common feature in other trematodes and perhaps other flatworms .
A spliced leader in Fasciola indicates that trans - splicing is likely to be a common feature in other trematodes and perhaps other flatworms .
A spliced leader in Fasciola indicates that trans - splicing is likely to be a common feature in other trematodes and perhaps other flatworms .
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