RNA silencing suppression by a second copy of the P1 serine protease of Cucumber vein yellowing ipomovirus, a member of the family Potyviridae that lacks the cysteine protease HCPro.

@article{Valli2006RNASS,
  title={RNA silencing suppression by a second copy of the P1 serine protease of Cucumber vein yellowing ipomovirus, a member of the family Potyviridae that lacks the cysteine protease HCPro.},
  author={Adrian Valli and Ana Montserrat Mart{\'i}n-Hern{\'a}ndez and Juan Jos{\'e} L{\'o}pez-Moya and Juan Antonio Garc{\'i}a},
  journal={Journal of virology},
  year={2006},
  volume={80 20},
  pages={10055-63}
}
The P1 protein of viruses of the family Potyviridae is a serine proteinase, which is highly variable in length and sequence, and its role in the virus infection cycle is not clear. One of the proposed activities of P1 is to assist HCPro, the product that viruses of the genus Potyvirus use to counteract antiviral defense mediated by RNA silencing. Indeed, an HCPro-coding region is present in all the genomes of members of the genera Potyvirus, Rymovirus, and Tritimovirus that have been sequenced… CONTINUE READING

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