RNA regulation of epigenetic processes

  title={RNA regulation of epigenetic processes},
  author={John S. A. Mattick and Paulo P. Amaral and M. Dinger and Tim R. Mercer and Mark F. Mehler},
There is increasing evidence that dynamic changes to chromatin, chromosomes and nuclear architecture are regulated by RNA signalling. Although the precise molecular mechanisms are not well understood, they appear to involve the differential recruitment of a hierarchy of generic chromatin modifying complexes and DNA methyltransferases to specific loci by RNAs during differentiation and development. A significant fraction of the genome‐wide transcription of non‐protein coding RNAs may be involved… 
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