RNA-quality control by the exosome

@article{Houseley2006RNAqualityCB,
  title={RNA-quality control by the exosome},
  author={Jonathan Houseley and John LaCava and David Tollervey},
  journal={Nature Reviews Molecular Cell Biology},
  year={2006},
  volume={7},
  pages={529-539}
}
Key PointsThe processing and degradation of RNA sequences is ubiquitous, and these activities can be separated into different classes on the basis of their mechanism and function. The clearest functional differences exist between RNA maturation that will generate a usable RNA from its precursor and RNA degradation that will destroy the RNA completely.There is mounting evidence that all RNA-maturation pathways in eukaryotes are continuously monitored by surveillance systems. A key component of… CONTINUE READING

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