RNA pseudoknots: Translational frameshifting and readthrough on viral RNAs

@article{Dam1990RNAPT,
  title={RNA pseudoknots: Translational frameshifting and readthrough on viral RNAs},
  author={Edwin B. Ten Dam and Cornelius W. A. Pleij and Leendert Bosch},
  journal={Virus Genes},
  year={1990},
  volume={4},
  pages={121-136}
}
Ribosomal frameshifting on retroviral RNAs has been proposed to be mediated by slippage of two adjacent tRNAs into the — 1 direction at a specific heptanucleotide sequence. Here we report a computer-aided analysis of the structure around the established or putative frameshift sites in a number of retroviral, coronaviral, toroviral, and luteoviral RNAs and two dsRNA yeast viruses. In almost all cases a stable hairpin was predicted four to nine nucleotides downstream of the shifty heptanucleotide… CONTINUE READING
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Showing 1-5 of 5 references

Nucleic Acid Domains and Proteins Involved in the Replication of Coronaviruses

  • P. J. Bredenbeek
  • PhD Thesis,
  • 1990
Highly Influential
5 Excerpts

Methods in Enzymology . RNA Processing . Part A . General Methods

  • L. Bosch, E. DahlbergJ., N. AbelsonJ.
  • 1989

Storm 0 G . D . and Gold L

  • R. RueckertR., S. McPheetersD.
  • 1988

The Control of HIV Gene Expression

  • H. D. Madhani, T. Jacks, R. Varmus H.E. in Franza, B. Cullen, F eds.Wong-Staal
  • Cold Spring Harbor, NY: Cold Spring Harbor…
  • 1988

Positive Strand Viruses

  • C.W.A. Pleij, J. P. Abrahams, A. van Belkum, K. Rietveld, M. A. Bosch L. in Brinton, R. R. Rueckert
  • UCLA Symposia on Molecular and Cellular Biology,
  • 1987
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