• Medicine, Biology
  • Published in
    Frontiers in bioscience : a…
    2008
  • DOI:10.2741/2975

RNA processing control in avian retroviruses.

@article{McNally2008RNAPC,
  title={RNA processing control in avian retroviruses.},
  author={Mark McNally},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2008},
  volume={13},
  pages={
          3869-83
        }
}
Upon integration into the host chromosome, retroviral gene expression requires transcription by the host RNA polymerase II, and viral messages are subject RNA processing events including 5'-end capping, pre-mRNA splicing, and polyadenylation. At a minimum, RNA splicing is required to generate the env mRNA, but viral replication requires substantial amounts of unspliced RNA to serve as mRNA and for incorporation into progeny virions as genomic RNA. Therefore, splicing has to be controlled to… CONTINUE READING

References

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