RNA polymerase III transcription deregulation : a study on Brf1 overexpression in prostate cancer

@inproceedings{Nam2013RNAPI,
  title={RNA polymerase III transcription deregulation : a study on Brf1 overexpression in prostate cancer},
  author={Noor Akmar Nam},
  year={2013}
}
RNA Polymerase III (Poll III) contributes to about 10% of nuclear transcription and is essential for the synthesis of short untranslated transcripts, including tRNA and 5S rRNA. Pol III deregulation has been implicated in driving cellular proliferation and transformation, along with increased expression of a number of Pol III specific transcription factors and transcripts. The significance of Pol III in clinical pathology, including that of human malignancies, remains to be formally tested… CONTINUE READING

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