RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

@inproceedings{Chan2014RNAmediatedPM,
  title={RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis},
  author={Ho Y. Chan},
  booktitle={Front. Cell. Neurosci.},
  year={2014}
}
Gene transcription produces a wide variety of ribonucleic acid (RNA) species in eukaryotes. Individual types of RNA, such as messenger, structural and regulatory RNA, are known to play distinct roles in the cell. Recently, researchers have identified a large number of RNA-mediated toxicity pathways that play significant pathogenic roles in numerous human disorders. In this article, we describe various common RNA toxicity pathways, namely epigenetic gene silencing, nucleolar stress… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS
9 Citations
124 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 124 references

Similar Papers

Loading similar papers…