RNA interference-mediated knockdown of brain-derived neurotrophic factor (BDNF) promotes cell cycle arrest and apoptosis in B-cell lymphoma cells.

@article{Xia2014RNAIK,
  title={RNA interference-mediated knockdown of brain-derived neurotrophic factor (BDNF) promotes cell cycle arrest and apoptosis in B-cell lymphoma cells.},
  author={Dajing Xia and Wentong Li and Li-sheng Zhang and Hongxian Qian and S Yao and Xia Qi},
  journal={Neoplasma},
  year={2014},
  volume={61 5},
  pages={523-32}
}
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin superfamily that has been reported to be involved in a number of neurological and psychological situations. Recently, high expression level of BDNF is observed in diverse human malignancies, delineating a role of BDNF in tumorigenesis. Nevertheless, its effect on B-cell lymphoma remains unclear. In this study, RNA interference technology mediated by short hairpin RNA (shRNA) was performed to inhibit endogenous BDNF… CONTINUE READING
4 Citations
33 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…