RNA interference in schistosomes: machinery and methodology.

@article{KrautzPeterson2010RNAII,
  title={RNA interference in schistosomes: machinery and methodology.},
  author={Greice Krautz-Peterson and Rita Bhardwaj and Zahra Faghiri and Cibele Aparecida Tararam and Patrick Skelly},
  journal={Parasitology},
  year={2010},
  volume={137 3},
  pages={485-95}
}
RNA interference (RNAi) is a potent gene silencing process that is playing an increasingly important role in investigations of gene function in schistosomes. Here we review what is known about the process in these parasites and provide an update on the methodology and machinery of RNAi. Data are presented to demonstrate that: (1) not all schistosome genes can be suppressed to the same extent, using the methods employed here; (2) while there is variation in the level of suppression achieved for… CONTINUE READING
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