RNA interference-based silencing of the alpha-amylase (amy1) gene in Aspergillus flavus decreases fungal growth and aflatoxin production in maize kernels

@article{Gilbert2018RNAIS,
  title={RNA interference-based silencing of the alpha-amylase (amy1) gene in Aspergillus flavus decreases fungal growth and aflatoxin production in maize kernels},
  author={Matthew K Gilbert and Rajtilak Majumdar and Kanniah Rajasekaran and Zhi-Yuan Chen and Qijian Wei and Christine M. Sickler and Matthew D Lebar and Jeffrey W. Cary and Bronwyn R. Frame and Kan Wang},
  journal={Planta},
  year={2018},
  volume={247},
  pages={1465-1473}
}
Main conclusionExpressing an RNAi construct in maize kernels that targets the gene for alpha-amylase in Aspergillus flavus resulted in suppression of alpha-amylase (amy1) gene expression and decreased fungal growth during in situ infection resulting in decreased aflatoxin production.Aspergillus flavus is a saprophytic fungus and pathogen to several important food and feed crops, including maize. Once the fungus colonizes lipid-rich seed tissues, it has the potential to produce toxic secondary… Expand
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