RNA in situ hybridization characterization of non-enzymatic derived bovine intervertebral disc cell lineages suggests progenitor cell potential.

@article{Kraus2017RNAIS,
  title={RNA in situ hybridization characterization of non-enzymatic derived bovine intervertebral disc cell lineages suggests progenitor cell potential.},
  author={Petra Kraus and Rachel Yerden and Victoria Kocsis and Thomas Lufkin},
  journal={Acta histochemica},
  year={2017},
  volume={119 2},
  pages={
          150-160
        }
}
Degeneration of the intervertebral disc (IVD) is a meritorious target for therapeutic cell based regenerative medicine approaches, however, controversy over what defines the precise identity of mature IVD cells and lack of single cell based quality control measures is of concern. Bos taurus and human IVDs are histologically more similar than is Mus musculus. The mature bovine IVD is well suited as model system for technology development to be translated into therapeutic cell based regenerative… CONTINUE READING
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