RNA gymnastics in mammalian signal recognition particle assembly

Abstract

More than one third of the cellular proteome is destined for incorporation into cell membranes or export from the cell. In all domains of life, the signal recognition particle (SRP) delivers these proteins to the membrane and protein traffic falls apart without SRP logistics. With the aid of a topogenic transport signal, SRP retrieves its cargo right at the… (More)
DOI: 10.1080/15476286.2014.996457

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