RNA-guided genome editing à la carte

Abstract

Two recent papers in Science illustrate how the prokaryotic CRISPR-Cas immune system machinery, which typically targets invasive genetic elements such as viruses and plasmids, can be converted into a sophisticated molecular tool for next-generation human genome editing. The versatile Cas9 RNA-guided endonuclease can be readily reprogrammed using… (More)
DOI: 10.1038/cr.2013.39

Topics

1 Figure or Table