RNA editing of a group II intron in Oenothera as a prerequisite for splicing

@article{Boerner1995RNAEO,
  title={RNA editing of a group II intron in Oenothera as a prerequisite for splicing},
  author={Gunter Boerner and Mario M{\"o}rl and Bernd Wissinger and Axel Brennicke and Carlo Schmelzer},
  journal={Molecular and General Genetics MGG},
  year={1995},
  volume={246},
  pages={739-744}
}
The trans-splicing group II intron c/d in the Oenothera mitochondrial nad1 gene is modified by RNA editing in domain 6. This C-to-U conversion generates the typical domain 6 structure, which prompted us to speculate that this RNA editing event might be essential for splicing. To test this hypothesis, we investigated the influence of unedited and edited sequences of the Oenothera intron on splicing in vitro. The stem of domain 6 of intron nad1-c/d was transplanted into the autocatalytic yeast… CONTINUE READING
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